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The incubation period of the hepatitis B virus is 75 days on average but can vary from 30 to 180 days.

virus is associated with acute viral hepatitis, an illness that begins with general ill-health, loss of appetite, nausea, vomiting, body aches, mild fever, and dark urine, and then progresses to development of jaundice.There are four known genes encoded by the genome, called C, X, P, and S.The core protein is coded for by gene C (HBc Ag), and its start codon is preceded by an upstream in-frame AUG start codon from which the pre-core protein is produced.A number of significant scientific events occurred in 2013, including the discovery of numerous Earthlike exoplanets, the development of viable lab-grown ears, teeth, livers and blood vessels, and the atmospheric entry of the most destructive meteor since 1908.The year also saw successful new treatments for diseases such as HIV, Usher syndrome and leukodystrophy, and a major expansion in the use and capabilities of technologies such as 3D printing and autonomous cars.These particles are not infectious and are composed of the lipid and protein that forms part of the surface of the virion, which is called the surface antigens (HBs Ag), and is produced in excess during the life cycle of the virus.

The genome of HBV is made of circular DNA, but it is unusual because the DNA is not fully double-stranded.

A few people may have a more severe form of liver disease known as (fulminant hepatic failure) and may die as a result.

The infection may be entirely asymptomatic and may go unrecognized.

The partially double-stranded DNA is rendered fully double-stranded by completion of the ( ) sense strand and removal of a protein molecule from the (−) sense strand and a short sequence of RNA from the ( ) sense strand.

Non-coding bases are removed from the ends of the (−) sense strand and the ends are rejoined.

virus either may be asymptomatic or may be associated with a chronic inflammation of the liver (chronic hepatitis), leading to cirrhosis over a period of several years.